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Interaction of cellulolytic enzymes with fungal cell wall polysaccharides
2025 - IRG/WP 25-11071
Wood rotting fungi are the primary agents responsible for the decomposition of wood in natural environments. These fungi secrete a variety of enzymes to degrade the chemically and structurally resistant components of the wood cell wall. Some of these enzymes possess a carbohydrate-binding module (CBM), which enhances enzymatic efficiency by increasing their affinity to the substrate. Previously, w...
K Fukabori, N Hattori, Y Kojima, R Iizuka, M Yoshida


Interaction between AA9 lytic polysaccharide monooxygenase and PQQ-dependent pyranose dehydrogenase in cellulose degradation
2025 - IRG/WP 25-11075
Wood-decaying fungi degrade cellulose, the primary polysaccharide in wood, as a nutrient source by utilising various hydrolytic and oxidative enzymes. Among these, lytic polysaccharide monooxygenase (LPMO9) has gained attention as a key enzyme that enhances the degradation efficiency of other cellulases. The activity of LPMO9 requires both electrons and hydrogen peroxide. It has been reported that...
H Murai, Y Kojima, E G Kommedal, V G H Eijsink, M Yoshida